Author
University of MinnesotaORCID 0000-0002-0741-6813Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Wei Kang Shi, G. M. Jonaid, Md. Golam Kibria, Jacob Allen, Hanqin Peng, Sophia Rits‐Volloch, Haisun Zhu, Shaowei Wang, Richard M. Walsh, Jianming Lu, Bing Chen
The paper reports a cryo-EM structure of the S2 fragment of SARS-CoV-2 after S2 cleavage, showing it represents a late fusion intermediate, and shows that S2 cleavage accelerates membrane fusion.
Nature Communications · Nov 27, 2025Peer-reviewedBiochemistry
Wei Kang Shi, Ming Chen, Yang Yang, Wei Zhou, Shiyun Chen, Yi Yang, Yangbo Hu, Bin Liu
This paper reports the cryo-EM structure of a SARS-CoV-2 RdRp complex and identifies a new potential drug target interface for antiviral design.
bioRxiv · Jul 30, 2020 · PreprintMolecular Biology
Wei Kang Shi, Wei Zhou, Baoyue Zhang, Shaojia Huang, Yanan Jiang, Abigail Schammel, Yangbo Hu, Bin Liu
The paper reveals how σ28-RNA polymerase recognizes DNA promoters through zinc binding domain interactions, enhancing transcription from weak σ4/-35 element promoters.
The EMBO Journal · Jun 2, 2020Peer-reviewedMolecular Biology
Wei Kang Shi, Yanan Jiang, Yibin Deng, Zigang Dong, Bin Liu
This study reports cryo-EM structures of E. coli class-II CAP-dependent transcription activation complexes, revealing conformational changes in RNAP induced by CAP binding.
PLoS Biology · Apr 20, 2020Peer-reviewedMolecular Biology