Ricardo Mallarino

Lactation Remodels the Maternal Lung to Promote Preemptive Innate Defense

This study shows lactation remodels the maternal lung to enhance innate defense against respiratory pathogens through epithelial changes, vascular remodeling, and granulocyte recruitment.

Patterns of Mitochondrial ATP Predict Tissue Folding

The paper shows mitochondrial ATP patterns predict tissue folding during embryonic development by analyzing mitochondrial distribution and energy dynamics in epithelial cells.

Agouti integrates environmental information to regulate natural variation in paternal behavior

The paper identifies Agouti as a molecular integrator of socio-environmental factors that influence paternal care in African striped mice.

Conservation, alteration, and redistribution of mammalian striatal interneurons

The paper analyzes the conservation and evolution of striatal interneurons across mammals, finding that TAC3 interneurons are conserved and that neuronal types evolve through redistribution and refinement.

Marsupial immune protection is shaped by enhancer sharing and gene cluster duplication of cathelicidin antimicrobial peptides

The paper investigates how marsupial neonates use cathelicidin antimicrobial peptides for immune protection through genomic clustering and enhancer sharing, showing their effectiveness in a sepsis model.

Convergent deployment of ancestral programs during the evolution of mammalian flight membranes

The paper shows that WNT5A and limb development genes are reused in the evolution of flight membranes across mammals.

A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice

The paper identifies Sfrp2 as a multifunctional regulator controlling coat pattern and color in African striped mice through transcriptomics, modeling, and gene editing.

A vascular origin for pulmonary smooth muscle in the avian lung

The paper identifies vascular smooth muscle as the developmental source of pulmonary smooth muscle in birds and shows PITX2 regulates this transition.

The fitness consequences of genetic variation in wild populations of mice

The paper investigates how genetic variation in wild mice affects fitness by linking genotype to phenotype and allele frequency changes through field and lab experiments.