Suoqin Jin

This study shows basophils promote inflammation resolution and wound healing in both adult and aged mice by driving tissue remodeling and immunoregulatory functions.

The paper introduces CellChat v2, a tool for analyzing cell-cell communication from single-cell and spatial transcriptomics data, including spatial proximity analysis and expanded ligand-receptor databases.

The paper identifies keratinocyte subpopulations in stable vitiligo skin that drive disease persistence through CXCL signaling and altered metabolism.

This study uses single-cell transcriptomics to identify novel motor neuron subtypes in mice, revealing subtype diversity that increases in land animals and continues to evolve in humans.

CellChat infers communication probabilities between cell groups using a mass-action model and 2,021 curated ligand-receptor interactions (multimeric complexes, cofactors), then compares signaling networks across scRNA-seq datasets.

SCOUT improves neuronal tracking in longitudinal calcium imaging by reducing motion artifacts and false discoveries, enabling analysis of neural ensemble dynamics over 60 days.

The paper uses single-cell transcriptomics to define basal cell states in skin homeostasis and wound healing, identifying distinct transcriptional states and their dynamics.