Ulrich Hofmann

Riboflavin-sensitized UVA collagen crosslinking produced a controllable, dose-dependent increase in the nanomechanical strength of ex vivo bovine dura mater

This study shows riboflavin-sensitized UVA crosslinking increases the mechanical strength of bovine dura mater in a dose-dependent manner.

In Search for Biomarkers Reflecting Neural Implant-Induced Tissue Response Dynamics

This study identifies a conserved ECM regulatory axis linking traumatic brain injury, spinal cord injury, and neural implant-induced injury through transcriptomic analysis, highlighting HA-DAMP signaling as a potential biomarker for monitoring implant biocompatibility.

Ex vivo Infrared Nerve Stimulation on the Rat Sciatic Nerve: Challenges and Pitfalls

This study presents an ex vivo infrared nerve stimulation setup for rat sciatic nerves, demonstrating compound action potential evocation and identifying key artifacts in the method.

Transcriptional characterization of the glial response due to chronic neural implantation of flexible microprobes

This study characterizes the transcriptional response of glial cells to chronic implantation of flexible microprobes over 18 weeks, showing initial activation and eventual partial normalization.

Bilateral Intracranial Beta Activity during Forced and Spontaneous Movements in a Hemi-PD Rat Model

The paper evaluates motor impairments and beta oscillations in a 6-OHDA rat PD model, finding high beta power as a biomarker and DBS as a performance enhancer.

Diversify your workflow! - An inconvenient suggestion to analyze spike data from intracranial recordings

The paper evaluates spike detection methods in intracranial recordings, showing inconsistencies due to varying pipelines and suggesting consensus-based event acceptance to improve reliability.

Inferring spatially transient gene expression pattern from spatial transcriptomic studies

SPATA bundles spatial transcriptomics analysis: spatially resolved expression, how transcriptional programs shift by region, and expression changes along spatial trajectories.

When the ostrich-algorithm fails: Blanking method affects spike train statistics

The paper quantifies how blanking during electrical stimulation affects spike train statistics, finding up to 27% spike loss at 130 Hz and 2 ms blanking window.

Mud sticks after all: Chronically implanted microelectrodes but not electrical stimulation cause c-fos expression along their trajectory

The paper shows that chronic implantation of microelectrodes, but not electrical stimulation, causes c-fos expression in surrounding neurons in rats.

When a rose is not a rose: Pyramidal neurons respond differently in healthy and epileptic human neocortex

The paper compares electrophysiological properties of pyramidal neurons in epileptic and non-epileptic human neocortex, finding reduced excitability in epileptic neurons due to increased K+ channel activity.