Steven M. Yellon

A two-dose DMA regimen on gestational day 15 prevented LPS-induced preterm birth in CD-1 mice, reversed cytokine surges within days, and spared term parturition.

This study investigates how progesterone loss affects cervical remodeling and preterm birth, finding that P4 treatment prevents preterm birth but causes dystocia, while loss of P4 response correlates with cervical ripening.

This study compares vaginal and intraperitoneal dimethylacetamide formulations in a mouse model of preterm birth, finding similar efficacy but lower systemic concentrations with vaginal delivery.