BiochemistrybioRxivPreprint
Fibroblast growth factor 21 regulates neuromuscular junctioninnervation through HDAC4 in denervation-induced skeletal muscle atrophy
Lirong Zheng, Takashi Sasaki, Liyang Ni…·Ryuichiro Sato
This study identifies FGF21 as a key driver of denervation-induced skeletal muscle atrophy through HDAC4 regulation, showing that inhibiting FGF21 could mitigate muscle atrophy.
DOI 10.1101/2025.02.18.638653