Kim Butts

Impact of acoustic property uncertainty on transcranial ultrasound simulation

This study quantifies how uncertainty in acoustic and thermal tissue properties affects transcranial ultrasound exposure estimates using simulations.

Ultrasonic local anesthetic uncaging enables noninvasive, targeted, and transient knock-out of brain function

This paper demonstrates SonoRopi, a noninvasive method using ultrasound to transiently inhibit brain function in mice and rats.

Dose-dependent ultrasound neuromodulation of the human brain

This study shows that ultrasound-induced tissue displacement predicts functional neuromodulation in the human brain during transcranial ultrasound stimulation.

MR-ARFI and Beyond: Characterizing the Temporal Dynamics of Acoustic Radiation Force in Human Brain

This paper characterizes the temporal dynamics of acoustic radiation force in human brain tissue using MR-ARFI, finding that stiffer tissue exhibits shorter time constants and reduced displacement.

Psychophysical validation of calibrated white-noise and tuned-noise auditory masks for transcranial focused ultrasound

This study validates auditory noise masks to reduce the perceptibility of transcranial ultrasound, finding that high masker levels are needed and spectrum-tuned masks do not outperform white noise.

Effects of transcranial focused ultrasound stimulation to human lateral geniculate nucleus on visual perception and steady-state visual evoked potentials

This study investigates the effects of transcranial focused ultrasound on visual perception and SSVEP in humans but finds no significant impact despite accurate targeting.

Noninvasive Diagnostic Ultrasound-Guided Focused Ultrasound Enables Selective, Reversible Inhibition of Peripheral Nociceptive Fibers and Prevents Acute Pain

This paper demonstrates that noninvasive ultrasound-guided focused ultrasound can selectively and reversibly inhibit peripheral nociceptive fibers and prevent acute pain in a rat model.

Parameter optimisation for mitigating somatosensory confounds during transcranial ultrasonic stimulation

This study identifies strategies to mitigate somatosensory confounds during transcranial ultrasonic stimulation by optimizing parameters such as pulse shaping and transducer settings.

Optimization of MR-ARFI for Human Transcranial Focused Ultrasound

This study optimizes MR-ARFI for human transcranial focused ultrasound to reduce exposure and improve motion robustness, demonstrating its potential for guiding neural therapeutics.

Transcranial Focused Ultrasound Neuromodulation of the Thalamic Visual Pathway in a Large Animal Model

This study uses MR-guided TUS to modulate visual evoked potentials and cortical oscillations in a sheep model by targeting the lateral geniculate nucleus.

Transcranial ultrasound selectively biases decision-making in primates

This study shows transcranial ultrasound can bias decision-making in non-human primates by modulating oculomotor circuits, with effects comparable to neuromodulatory drugs.

Elimination of peripheral auditory pathway activation does not affect motor responses from ultrasound neuromodulation

This study shows that motor responses from ultrasound neuromodulation are not caused by peripheral auditory pathway activation, using deaf mice and modified ultrasound stimuli.

Physical mechanisms of ultrasonic neurostimulation of the retina

This study identifies radiation force as the physical mechanism of ultrasonic neurostimulation in ex vivo salamander retina, showing frequency-dependent stimulation and standing wave effects.