Developmental BiologybioRxivPreprint
The long noncoding RNA Hand2as orchestrates heart development through regulation of precise expression of HAND2
Xue Han, Jiejie Zhang, Yaxi Liu…·Xiaohua Shen
This study identifies Hand2as as a key lncRNA regulating HAND2 expression in heart development through single-cell RNA sequencing and knockout models, leading to congenital defects and perinatal lethality.
DOI 10.1101/475723