Author

Joshua Victor

University of VermontORCID 0000-0002-6304-898XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Jiyong HongiD· 2 shared NIMRAT CHATTERJEEiD· 2 shared Pei ZhouiD· 2 shared Aarzoo Grover· 1 shared Andrew CromptoniD· 1 shared Ava SiegeliD· 1 shared Daniel AlmsteadiD· 1 shared Dmitry M. KorzhneviD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Jiyong HongORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 6, 2026

Targeting REV1 Exposes Context-Dependent Therapeutic Responses in Colorectal Cancer

Vihit Gupta, Madison Guyette, Sombodhi Bhattacharya…·NIMRAT CHATTERJEE

This study shows that targeting REV1 in colorectal cancer enhances chemotherapy sensitivity in a context-dependent manner and inhibits organoid growth.

DOI 10.64898/2026.11.04.764315

humanorganoid / primary culture

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GeneticsOpen BiologyPeer-reviewedDec 1, 2025

REV1 inhibition enhances trinucleotide repeat mutagenesis

Ava Siegel, Daniel Almstead, Naveen Kothandaraman…·Nimrat Chatterjee

This study shows that inhibiting REV1, a TLS polymerase, increases trinucleotide repeat instability in human cells, suggesting REV1 protects against TNR mutagenesis.

2 citations

humanexperimental assay

𝕏 PostBluesky