Mariusz Sacharczuk

This study shows that the HNF4A Q164X mutation impairs transcriptional activity in vitro but reduces liver tumorigenesis in heterozygous mice.

Adera is a deep learning model for drug repurposing in neuro-immunological diseases, achieving high accuracy in predicting drug targets.

The paper develops a deep neural network to predict epitopes from TCR beta-chain CDR3 sequences, achieving 98% accuracy using VDJdb and McPAS-TCR datasets.