Author

Coleman R. Harris

Vanderbilt UniversityORCID 0000-0002-6325-0694Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Eliot T. McKinleyiD· 2 shared Joseph T. RolandiD· 2 shared Ken S. LauiD· 2 shared Martha J. ShrubsoleiD· 2 shared Robert J. CoffeyiD· 2 shared Simon VandekariD· 2 shared Cody N. HeiseriD· 1 shared Ellie L. PingryiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Eliot T. McKinleyORCID

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2 papers

Recent·Most cited

Consensus tissue domain detection in spatial -omics data using MILWRM

Harsimran Kaur, Cody N. Heiser, Eliot T. McKinley, Lissa Ventura‐Antunes, Coleman R. Harris, Joseph T. Roland, Melissa A. Farrow, Hilary J. Selden, Ellie L. Pingry, John F. Moore, Lauren I. R. Ehrlich, Martha J. Shrubsole, Jeffrey M. Spraggins, Robert J. Coffey, Ken S. Lau, Simon Vandekar

The paper introduces MILWRM, a tool for detecting tissue domains in spatial-omics data, and demonstrates its application in human colonic polyps and mouse brain slices.

Communications Biology · Oct 30, 2024Peer-reviewedSystems Biology

Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images

Coleman R. Harris, Eliot T. McKinley, Joseph T. Roland, Qi Liu, Martha J. Shrubsole, Ken S. Lau, Robert J. Coffey, Julia Wrobel, Simon Vandekar

This paper quantifies slide-to-slide variation in multiplexed immunofluorescence data and introduces normalization methods to correct it, showing that dividing by slide mean and functional data registration perform best.

Bioinformatics · Dec 31, 2021Peer-reviewedBioinformatics