Lissa Ventura‐Antunes

The paper investigates Serpin A3 expression in cerebral amyloid angiopathy and Alzheimer's disease using single-nucleus transcriptomics and microscopy, finding increased Serpin A3 in affected tissues.

The paper maps lipid microenvironments in human brain vasculature using multimodal imaging and identifies lipid markers associated with cerebral amyloid angiopathy.

This paper introduces a multimodal pipeline for spatiomolecular analysis of tissue samples, demonstrating its application in Alzheimer's disease and type 2 diabetes.

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

The paper introduces MILWRM, a tool for detecting tissue domains in spatial-omics data, and demonstrates its application in human colonic polyps and mouse brain slices.

This study links β-amyloid deposition and lysyl oxidase to arteriolar degeneration and stiffness in cerebral amyloid angiopathy using post-mortem human brain tissue analysis.

The paper examines capillary density in the mouse brain and finds it is mostly homogeneous, with energy supply per neuron decreasing as neuronal density increases.