BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Ultra-slow conformational dynamics and catch bond formation of a Bacterial Adhesin revealed by a single-domain variant of FimH.
Pearl Magala, Lisa M. Tuttle, Gianluca Interlandi…·Rachel E. Klevit
This study investigates FimH conformational dynamics and catch bond formation using a single-domain variant, revealing ultra-slow dynamics and a dynamic allosteric mechanism.