Author

Kejia Kan

Heidelberg UniversityORCID 0000-0002-6340-1990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:benchmarking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Fengjiao Zhu· 2 shared Lina Wang· 2 shared Ning WuiD· 2 shared Shuai NiiD· 2 shared Wei Wang· 2 shared Carsten StichtiD· 1 shared Chen ShaoiD· 1 shared Chenhao Tong· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Fengjiao Zhu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systematic In Silico Off-Target Assessment of siRNAs: Integrated Tissue-Specific Scoring and Cross-Species Preclinical Model Selection with TargetSureR

Shuai Ni, Kejia Kan, Fengjiao Zhu, Lina Wang, Wei Wang, Ning Wu

TargetSureR assesses siRNA off-target risks using a seven-dimensional scoring system and enables cross-species model selection for preclinical safety evaluation.

bioRxiv · May 31, 2026 · PreprintBioinformatics

LISA: A Comprehensive R Package for Lentiviral Integration Site Analysis in Gene Therapy Safety Assessment

Shuai Ni, Ning Wu, Yun Jee Kang, Fengjiao Zhu, Jueyu Wang, Lina Wang, Wei Wang, Heng Mei, Kejia Kan

LISA is an R package for analyzing lentiviral integration sites in gene therapy to assess safety by identifying risk-associated genomic regions and tracking clonal dynamics.

bioRxiv · Dec 23, 2025 · PreprintBioinformatics

FOXA2 is essential for maintaining the urea cycle in acute liver failure

Rilu Feng, Rui Liu, Chenhao Tong, Tao Lin, Xiaofeng Li, Hui Liu, Chen Shao, Kejia Kan, Carsten Sticht, Yujia Li, Sai Wang, Stefan Munker, Ulrich Wirth, Hanno Nieß, Roman Liebe, , Honglei Weng

This study identifies FOXA2's role in maintaining urea cycle function in acute liver failure by regulating CPS1 transcription and preventing hyperammonemia.

bioRxiv · Dec 11, 2023 · PreprintMolecular Biology