Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease
Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Lea Berger, Cyrill Géraud, Ye Yao, Frederik Link, Chenhao Tong, Zeribe C. Nwosu, Pia Erdoesi, Weronika Piorońska, Kerry Gould, Christoph Meyer, Rilu Feng, , Sai Wang
This study identifies EGF/STAT1 and IFNγ/NRF2 signaling pathways regulating ECM1 expression, showing their role in maintaining liver homeostasis versus promoting chronic liver disease.
bioRxiv · Feb 17, 2024 · PreprintCell Biology