Author

Jeff S. McDermott

Eli Lilly (United States)ORCID 0000-0002-6362-3307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:electronic health records· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:rat· 1

Frequent Co-Authors

Jeffrey L. KrajewskiiD· 3 shared Annemarie DedekiD· 2 shared Eve Chung TsaiiD· 2 shared Michael E. HildebrandiD· 2 shared Ariel J. LevineiD· 1 shared Baolin Li· 1 shared Chris RudykiD· 1 shared Clare Murray-Lawson· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Jeffrey L. KrajewskiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Expression and localization of NMDA receptor GluN2 subunits in dorsal horn pain circuits across sex, species, and late postnatal development

Katherine Griffiths, Jennifer Armstrong, Newton Martin, Clare Murray-Lawson, Estefania O’neil, Laurence S. David, Santina Temi, Jessica Parnell, Chris Rudyk, Julia Bursey, Jeffrey L. Krajewski, Jeff S. McDermott, Annemarie Dedek, Ariel J. Levine, Baolin Li, , Michael E. Hildebrand

The paper investigates the expression and localization of NMDA receptor GluN2 subunits in dorsal horn pain circuits across sex, species, and development, finding conserved expression but species- and development-specific localization patterns.

Journal of Neuroscience · May 21, 2026Peer-reviewedNeuroscience

Processing and sectioning of organ donor spinal cord tissue for electrophysiology on acute human spinal cord slices

Annemarie Dedek, Eder Gambeta, Raksha Shriraam, Emine Topcu, Jeff S. McDermott, Jeffrey L. Krajewski, Eve Chung Tsai, Michael E. Hildebrand

This paper describes a protocol for preparing viable human spinal cord slices for acute electrophysiological recordings to bridge the translational gap between rodent models and human patients.

Brain Communications · Jan 1, 2026Peer-reviewedNeuroscience

Preferential Pharmacological Inhibition of Nav1.6, but not Nav1.1, Abolishes Epileptiform Activity Induced by 4-AP in Mouse Cortical Slices

Reesha R. Patel, Xingjie Ping, Shaun R. Patel, Jeff S. McDermott, Jeffrey L. Krajewski, Xian Xuan Chi, Eric S. Nisenbaum, Xiaoming Jin, Theodore Cummins

This study investigates the effects of inhibiting specific voltage-gated sodium channel isoforms on epileptiform activity in mouse cortical slices, finding that Nav1.6 inhibition is more effective than Nav1.1 inhibition.

bioRxiv · May 29, 2020 · PreprintNeuroscience