Cancer BiologyRedox BiologyPeer-reviewed
PRPS activity tunes redox homeostasis in Myc-driven lymphoma
Austin C. MacMillan, Bibek Karki, Juechen Yang…·John T. Cunningham
This study identifies PRPS2 as a key regulator of redox homeostasis in Myc-driven lymphomas, showing that its inactivation causes reductive stress and cell death.
8 citations