Author

Karmela R. Gertz

University of CincinnatiORCID 0000-0002-8025-5489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Austin C. MacMillaniD· 1 shared Bibek KarkiiD· 1 shared Jarek MelleriD· 1 shared Jay A. PateliD· 1 shared John T. CunninghamiD· 1 shared Juechen YangiD· 1 shared Maria Czyzyk-KrzeskaiD· 1 shared Samantha ZumwaldeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Austin C. MacMillanORCID

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1 paper

Recent·Most cited

PRPS activity tunes redox homeostasis in Myc-driven lymphoma

Austin C. MacMillan, Bibek Karki, Juechen Yang, Karmela R. Gertz, Samantha Zumwalde, Jay A. Patel, Maria Czyzyk-Krzeska, Jarek Meller, John T. Cunningham

This study identifies PRPS2 as a key regulator of redox homeostasis in Myc-driven lymphomas, showing that its inactivation causes reductive stress and cell death.

Redox Biology · Apr 25, 2025Peer-reviewedCancer Biology