Author
National Institutes of HealthORCID 0000-0002-6371-7530Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Megan M. Shuey, Kyung Min Lee, Jacob M. Keaton…·Todd L. Edwards
This paper develops a genetically informed drug-repurposing pipeline for diabetes using EHRs and validates two anti-hypertensive classes as glycemic regulators.
Jacob Joseph, Chang Liu, Qin Hui…·Yan V. Sun
This study compares the genetic architecture of heart failure with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF), finding distinct genetic associations and highlighting HFpEF's heterogeneity.
Marijana Vujković, Jacob M. Keaton, Julie Ann Lynch…·Saib S. Gappy
Multi-ethnic type 2 diabetes (T2D) meta-analysis of 228,499 cases and 1,178,783 controls finds 318 previously unreported loci, 804 expression-colocalized genes, and 13 SNP-by-T2D vascular-outcome interactions.
Yanfei Zhang, Kevin Ho, Jacob M. Keaton…·Ming Ta Michael Lee
This paper identifies novel genetic variants associated with PCOS using EHR-based GWAS and validates them in independent cohorts.