Author

Olena Trofimyuk

Weizmann Institute of ScienceORCID 0000-0002-6380-1337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Ekaterina Kopitman· 2 shared Milana Fraiberg· 2 shared Zvulun ElazariD· 2 shared Alik Demishtein· 1 shared Bat Chen Tamim-Yecheskel· 1 shared Dan S. TawfikiD· 1 shared Elena AinbinderiD· 1 shared Fanindra Kumar DeshmukhiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Ekaterina Kopitman

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3 papers

Recent·Most cited

TECPR2 maintains mitochondrial homeostasis in neurodegeneration

Madhuri Chaurasia, Milana Fraiberg, Nemanja Subic, Oren Shatz, Kamilya Kokabi, Olee Gogoi, Olena Trofimyuk, Bat Chen Tamim-Yecheskel, Saskia Freud, Alik Demishtein, Ekaterina Kopitman, Inna Goliand, Sabita Chourasia, Yoav Peleg, Elena Ainbinder, , Zvulun Elazar

This study shows that TECPR2 loss causes mitochondrial dysfunction and mitophagy impairment in HSAN9, which can be mitigated by ISR suppression.

bioRxiv · Sep 4, 2025 · PreprintCell Biology

A new cellular platform for studying autophagy

Korina Goldin-Azulay, Milana Fraiberg, Olena Trofimyuk, Yishai Levin, Nina Bacher Reuven, Ekaterina Kopitman, Zvulun Elazar

This paper introduces a CRISPR-based platform to study GABARAP proteins in autophagy, revealing their distinct associations with autophagosomes.

Journal of Biological Chemistry · Oct 19, 2024Peer-reviewedCell Biology

Helicase-Like Functions in Phosphate Loop Containing Beta-Alpha Polypeptides

Pratik Vyas, Olena Trofimyuk, Liam M. Longo, Fanindra Kumar Deshmukh, Michal Sharon, Dan S. Tawfik

This study demonstrates that simple polypeptides with P-loop motifs can exhibit helicase-like activities, suggesting they may represent early precursors to complex P-loop NTPases.

Proceedings of the National Academy of Sciences · Apr 12, 2021Peer-reviewedMolecular Biology