Alexander Mellmann

This study shows that innate immune memory in hosts does not increase average virulence but increases variation in virulence among pathogens evolved in primed hosts.

This paper evaluates recent improvements in Oxford Nanopore sequencing for bacterial genomic surveillance, showing that new software tools significantly enhance accuracy and reproducibility.

The paper evaluates a real-time plasmid transmission detection pipeline integrated into SeqSphere+ software, showing it can detect plasmid clusters and early warning alerts effectively using long-read sequencing data.

The paper compares core genome MLST (cgMLST) with CE-PCR ribotyping and SNP analysis for C. difficile typing, finding cgMLST offers better discrimination but may require adjusted thresholds for outbreak detection.