Konstantin V. Pervushin

This paper introduces an AI-driven framework for improving NMR spectroscopy resolution by treating 2D spectra as video sequences and using super-resolution techniques to enhance cross-peak clarity.

This study shows that the C-terminal domain of coronavirus E protein can modulate liposome shape by forming amyloid fibers, suggesting a mechanism for membrane interaction in host cells.

This paper investigates the structural organization of peptide coacervate microdroplets using spectroscopy and microscopy, revealing dynamic interactions and cargo sequestration mechanisms.

The paper uses liquid-liquid phase separation to protect amyloidogenic peptides from aggregation during expression and purification.

The paper shows that trisomy 21 cerebral organoids exhibit AD-like pathology, which can be suppressed by BACE2 trisomy and inhibited by BACE1 inhibitors, suggesting BACE2 as an AD-suppressor gene.

This study shows xenobiotics like Chlorpheniramine and 9,10-PQ interact with L-PGDS and Aβ amyloids, increasing fibril cytotoxicity and potentially linking xenobiotic exposure to Alzheimer's disease risk.