Author

Agueda A. Rostagno

New York UniversityORCID 0000-0002-6817-2074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

John HardyiD· 2 shared Jorge A. GhisoiD· 2 shared André StrydomiD· 1 shared Anne Rovelet‐LecruxiD· 1 shared Annette Karmiloff‐Smith· 1 shared Aoife MurrayiD· 1 shared Carla Marie StartiniD· 1 shared Charles ArberiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

John HardyORCID

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2 papers

Recent·Most cited

NeuroscienceActa NeuropathologicaPeer-reviewedNov 15, 2024

Microglia produce the amyloidogenic ABri peptide in familial British dementia

Charles Arber, Jackie M. Casey, Samuel Crawford…·Selina Wray

This study shows microglia produce ABri peptide in FBD, contributing to amyloid plaques and neurodegeneration, and suggests ITM2B/BRI2 is involved in microglial disease responses.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceMolecular PsychiatryPeer-reviewedJul 9, 2020

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain

Ivan Alić, Pollyanna Agnes Goh, Aoife Murray…·Henrik Zetterberg

The paper shows that trisomy 21 cerebral organoids exhibit AD-like pathology, which can be suppressed by BACE2 trisomy and inhibited by BACE1 inhibitors, suggesting BACE2 as an AD-suppressor gene.

123 citationstop 1%

humanproteomics

𝕏 PostBluesky