Author

Anne Rovelet‐Lecrux

InsermORCID 0000-0003-4454-3659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Agueda A. RostagnoiD· 1 shared André StrydomiD· 1 shared Annette Karmiloff‐Smith· 1 shared Aoife MurrayiD· 1 shared Carla Marie StartiniD· 1 shared David KoschutiD· 1 shared David Laurence BeckeriD· 1 shared David WalloniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Agueda A. RostagnoORCID

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1 paper

Recent·Most cited

NeuroscienceMolecular PsychiatryPeer-reviewedJul 9, 2020

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain

Ivan Alić, Pollyanna Agnes Goh, Aoife Murray…·Henrik Zetterberg

The paper shows that trisomy 21 cerebral organoids exhibit AD-like pathology, which can be suppressed by BACE2 trisomy and inhibited by BACE1 inhibitors, suggesting BACE2 as an AD-suppressor gene.

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humanproteomics

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