Author

Adrian C. Johnston

Johns Hopkins UniversityORCID 0000-0002-6394-3765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ashleigh J. CrawfordiD· 2 shared Denis WirtziD· 2 shared Praful R. NairiD· 2 shared Wenxuan DuiD· 2 shared André ForjaziD· 1 shared Ashley L KiemeniD· 1 shared Ashley Tang· 1 shared Bryan Zhou· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

Ashleigh J. CrawfordORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Reports MethodsPeer-reviewedFeb 1, 2026

A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity

Eban A. Hanna, Ashleigh J. Crawford, Wenxuan Du…·Denis Wirtz

This paper introduces a 3D in vitro assay to study immune cell infiltration and cytotoxicity in solid tumors, showing it captures key steps of immune cell interaction with the tumor microenvironment.

7 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 16, 2024

High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment

Wenxuan Du, Bryan Zhou, André Forjaz…·Denis Wirtz

This study identifies high-motility tumor-associated monocytes (TAMos) that drive macrophage infiltration and cancer cell proliferation via IL-6 and MAPK pathways, suggesting IL-6 as a therapeutic target.

6 citations

mouseproteomics

𝕏 PostBluesky