Author

Chien‐Ling Huang

Hong Kong Polytechnic UniversityORCID 0000-0002-6396-5649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Raymond C.B. WongiD· 3 shared Alex William HewittiD· 2 shared Cat Binh Nguy· 2 shared Chi D. LuuiD· 2 shared Daniel Urrutia-CabreraiD· 2 shared Genevieve Huppert· 2 shared Jiang-Hui WangiD· 2 shared Keith R G MartiniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Raymond C.B. WongORCID

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3 papers

Recent·Most cited

Molecular BiologyMolecular Therapy AdvancesPeer-reviewedJul 3, 2026

Optimization of AAV tools to target Muller glial cells for retinal gene therapy

Daniel Urrutia-Cabrera, Genevieve Huppert, Stephanie Chu…·Raymond C.B. Wong

This study optimizes AAV serotypes and promoters to specifically target Muller glial cells in rats, identifying ShH10Y and GFAP promoter as the most effective combination for in vivo delivery.

DOI 10.1016/j.omta.2026.201804

ratexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintApr 11, 2026

Optimization of AAV tools to target Müller glial cells for retinal gene therapy

Daniel Urrutia-Cabrera, Genevieve Huppert, Stephanie Chu…·Raymond C.B. Wong

This study optimizes AAV serotypes and promoters to specifically target Müller glial cells in rats, identifying ShH10Y and GFAP promoter as the most effective combination for in vivo delivery.

DOI 10.64898/2026.04.09.717359

rathuman

𝕏 PostBluesky

Systems BiologybioRxivPreprintMay 18, 2025

CNVPipe: An enhanced pipeline for accurate analysis of copy number variation from whole-genome sequencing

Jiahong Sun, Nonthaphat Kent Wong, Zhiwei Jiang…·Chien‐Ling Huang

CNVPipe improves CNV detection in WGS by integrating CNV tools with machine learning, reducing FDR and increasing sensitivity for both bulk and single-cell data.

DOI 10.1101/2025.05.18.654763

whole-genome sequencingmachine learning (classical)

𝕏 PostBluesky