Non-autonomous regulation of germline stem cell proliferation bysomatic MPK-1/MAPK activity in C. elegans
Sarah Robinson-Thiewes, Benjamin Dufour, Pier-Olivier Martel, Xavier Lechasseur, Amani Ange Danielle Brou, Vincent Roy, Yunqing Chen, Judith E. Kimble, Patrick Narbonne
The paper identifies tissue-specific MPK-1 isoforms in C. elegans and shows that the soma-specific MPK-1A promotes germline stem cell proliferation non-autonomously.
Cell Reports · May 1, 2021Peer-reviewedDevelopmental Biology