Sarah Robinson-Thiewes

BRD4 recruitment desilences transcription without erasure or depletion of repressive chromatin

This study shows that BRD4 recruitment can desilence transcription within repressive chromatin without removing H3K9me3 or HP1, challenging conventional models of chromatin regulation.

A sensitized genetic screen to identify regulators of C. elegans germline stem cells

The paper identifies genes that function redundantly with lst-1 or sygl-1 to maintain C. elegans germline stem cells through genetic screens.

Non-autonomous regulation of germline stem cell proliferation bysomatic MPK-1/MAPK activity in C. elegans

The paper identifies tissue-specific MPK-1 isoforms in C. elegans and shows that the soma-specific MPK-1A promotes germline stem cell proliferation non-autonomously.

Two classes of active transcription sites and their roles in developmental regulation

The paper identifies two classes of active transcription sites (iATS and cATS) in C. elegans and shows their differential contribution to transcriptional output during development.