Author

Xavier Lechasseur

Université du Québec à Trois-Rivières

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Benjamin Dufour· 2 shared Patrick NarbonneiD· 2 shared Pier-Olivier MarteliD· 2 shared Alexandre ClouetiD· 1 shared Alexane Murray· 1 shared Amani Ange Danielle Brou· 1 shared Aurelia Condomat Zoumabo· 1 shared Janina Rieger· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Benjamin Dufour

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2 papers

Recent·Most cited

Non-autonomous PMK-1/p38 MAPK signaling ensures homeostatic downregulation of germline stem cell proliferation in C. elegans

Alexandre Clouet, Matthieu Valet, Benjamin Dufour, Janina Rieger, Xavier Lechasseur, Aurelia Condomat Zoumabo, Lloyd Venceslas Fotso Dzuna, Alexane Murray, Jichao Deng, Pier-Olivier Martel, Patrick Narbonne

The paper identifies a signaling pathway in C. elegans that downregulates germline stem cell proliferation in response to oocyte usage needs, preventing tumor formation.

bioRxiv · Sep 24, 2025 · PreprintCell Biology

Non-autonomous regulation of germline stem cell proliferation bysomatic MPK-1/MAPK activity in C. elegans

Sarah Robinson-Thiewes, Benjamin Dufour, Pier-Olivier Martel, Xavier Lechasseur, Amani Ange Danielle Brou, Vincent Roy, Yunqing Chen, Judith E. Kimble, Patrick Narbonne

The paper identifies tissue-specific MPK-1 isoforms in C. elegans and shows that the soma-specific MPK-1A promotes germline stem cell proliferation non-autonomously.

Cell Reports · May 1, 2021Peer-reviewedDevelopmental Biology