Author

Dien Ye

University of KentuckyORCID 0000-0002-6433-5032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:non-human primate· 1

Frequent Co-Authors

Alan DaughertyiD· 3 shared Hong S. LuiD· 3 shared A.H. Jan DanseriD· 2 shared Adam E. MullickiD· 2 shared Congqing WuiD· 2 shared Zhenyu LiiD· 2 shared Deborah A. HowattiD· 1 shared Hisashi SawadaiD· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMolecular Biology

Alan DaughertyORCID

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3 papers

Recent·Most cited

Renal Angiotensinogen in Nonhuman Primates is Predominantly Liver-Derived

Masayoshi Kukida, Lei Cai, Dien Ye, Hisashi Sawada, Yuriko Katsumata, Michael Franklin, Peter I. Hecker, Kenneth S. Campbell, A.H. Jan Danser, Adam E. Mullick, Alan Daugherty, Ryan E. Temel, Hong S. Lu

This study shows that renal angiotensinogen in nonhuman primates is mainly derived from the liver, as evidenced by reduced renal AGT levels after liver-specific AGT inhibition.

Arteriosclerosis Thrombosis and Vascular Biology · Sep 9, 2021Peer-reviewedMolecular Biology

GSDMD Deficiency Protects Against Aortic Rupture

Dien Ye, Deborah A. Howatt, Zhenyu Li, Alan Daugherty, Hong S. Lu, Congqing Wu

This study shows that GSDMD deficiency prevents aortic rupture in mice induced by AngII or BAPN, without affecting aortic dilation.

bioRxiv · Jan 8, 2021 · PreprintMolecular Biology

Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression: Insights into COVID-19

Congqing Wu, Dien Ye, Adam E. Mullick, Zhenyu Li, A.H. Jan Danser, Alan Daugherty, Hong S. Lu

This study investigates whether renin-angiotensin inhibition affects ACE2 and TMPRSS2 expression in mice, finding no changes in ACE2 but a decrease in TMPRSS2 in lungs with AGT depletion.

Hypertension · Jul 15, 2020Peer-reviewedMolecular Biology