Author

Benedikt Seligmann

Helmholtz Centre for Infection ResearchORCID 0009-0005-2923-0701Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Anika SteffeniD· 1 shared Christian SiebeniD· 1 shared Enyu XieiD· 1 shared Jakob FrankeiD· 1 shared Jennifer M. FrickeiD· 1 shared Klemens RottneriD· 1 shared Mai HuynhiD· 1 shared Maren SchubertiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Anika SteffenORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedAug 31, 2026

Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells

Enyu Xie, Maren Schubert, Jennifer M. Fricke…·Christian Sieben

This study shows that Arp2/3 complex-dependent actin remodeling is necessary for efficient RSV uncoating in A549 cells, as Arp2 knockout cells exhibit reduced infection and viral mRNA expression.

DOI 10.1128/jvi.01117-26

humanproteomics

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BioengineeringJournal of BiotechnologyPeer-reviewedMar 17, 2026

Production of the anticancer drug intermediate strictosidinic acid in engineered yeast

Benedikt Seligmann, Shenyu Liu, Mai Huynh…·Jakob Franke

This paper engineers yeast to produce strictosidinic acid, a key anticancer drug intermediate, achieving 548 mg/L through metabolic pathway optimization and strain engineering.

6 citationstop 1%

yeastmetabolomics

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