Author

Constantin Cretu

Universitätsmedizin GöttingenORCID 0000-0002-6466-176XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Csaba Zoltán Kibédi Szabó· 2 shared Julia PreobraschenskiiD· 2 shared Tobias MoseriD· 2 shared Vladimir PeñaiD· 2 shared Abigail Trebilcock· 1 shared Aleksandar CherneviD· 1 shared Carolin WichmanniD· 1 shared Constantin PapeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Csaba Zoltán Kibédi Szabó

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2 papers

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedOct 15, 2025

Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing

Han Chen, Constantin Cretu, Abigail Trebilcock…·Tobias Moser

The paper investigates the structure and function of otoferlin, showing how it binds Ca2+ and facilitates synaptic vesicle fusion in inner hair cells.

5 citations

mouseexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJan 25, 2025

Structural Basis of Lipid Membrane Binding by Human Ferlins

Constantin Cretu, Aleksandar Chernev, Csaba Zoltán Kibédi Szabó…·Julia Preobraschenski

This study determines the cryo-EM structures of human myoferlin and dysferlin bound to Ca2+ and lipids, revealing how their domain dynamics enable membrane binding and fusion.

1 citation

humancryo-EM

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