Author

Zhiyong Shao

Fudan UniversityORCID 0000-0002-6475-7681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Jiale FaniD· 2 shared Yanjun ShiiD· 2 shared Cuiying CheniD· 1 shared Danfeng SheniD· 1 shared Daniel A. Colón‐RamosiD· 1 shared Dingxia FengiD· 1 shared Guiqin SuniD· 1 shared Jichang HuangiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Jiale FanORCID

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Author profile →

4 papers

Recent·Most cited

Down regulation of Engase in Caenorhabditis elegans may improve its stresses adaptivity

Xinrong Lu, Yongliang Tong, Mengting Wu, Shaoxian Lyu, Jiale Fan, Junyu Zheng, Lin Zou, Danfeng Shen, Lin Rao, Linlin Hou, Cuiying Chen, Xunjia Cheng, Guiqin Sun, Zhiyong Shao, Li Chen

This study shows that downregulating CeEngase in C. elegans enhances its adaptability to heat and osmotic stress.

Cells Tissues Organs · May 10, 2025Peer-reviewedBiochemistry

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

Dingxia Feng, Zhiwei Zhai, Zhiyong Shao, Yi Zhang, Jo Anne Powell‐Coffman

The paper identifies crosstalk between SKN-1/NRF and HIF-1 in C. elegans, showing SKN-1 inhibits HIF-1 through EGL-9 regulation.

PLoS ONE · Jul 9, 2021Peer-reviewedGenetics

Gut regulates brain synaptic assembly through neuroendocrine signaling pathway

Yanjun Shi, Qin Lu, Zhiyong Shao

This study identifies a Wnt-endocrine pathway in the gut that regulates synaptic development in the brain via neuropeptide signaling in C. elegans.

bioRxiv · Jan 29, 2021 · PreprintNeuroscience

ADAMTS-family protease MIG-17 regulates synaptic allometry by modifying the extracellular matrix and modulating glia morphology during growth

Tingting Ji, Kai Wang, Jiale Fan, Jichang Huang, Mengqing Wang, Xiaohua Dong, Yanjun Shi, Laura Manning, Xumin Zhang, Zhiyong Shao, Daniel A. Colón‐Ramos

The paper identifies MIG-17, a secreted metalloprotease, as a regulator of synaptic allometry in C. elegans by modifying the extracellular matrix and glia morphology during growth.

bioRxiv · Aug 16, 2019 · PreprintNeuroscience