Amparo Querol

GeNETop: Context-Specific Genome-Scale Constrained Models Using Network Topology, Flux Variability, and Transcriptomics

GeNETop improves context-specific metabolic models by integrating flux variability, network topology, and transcriptomics to enable dynamic simulations.

Identification of a crucial INO2 allele for enhancing ethanol resistance in an industrial fermentation strain of Saccharomyces cerevisiae

The paper identifies an INO2 allele variant that enhances ethanol resistance in a yeast strain through lipid synthesis regulation.

Chromosome III aneuploidy enhances ethanol tolerance in industrial Saccharomyces cerevisiae by increasing TUP1 expression

The paper identifies TUP1 as a key gene responsible for ethanol tolerance in yeast strains with chromosome III aneuploidy.

Optogenetic control of a horizontally acquired region in yeast prevent stuck fermentations

This study uses optogenetics to show that region A genes in wine yeast are essential for completing fermentation under low nitrogen conditions.

Understanding brewing trait inheritance in de novo lager yeast hybrids

This study investigates hybridization success and fermentation traits in lager yeast hybrids, finding that parental lineages influence volatile compound profiles and phenotypic variability.

A continuous dynamic genome-scale model explains batch fermentations led by species of the Saccharomyces genus.

This paper introduces a continuous dynamic genome-scale model to predict intracellular fluxes during batch fermentation, capturing all growth phases and secondary metabolism in Saccharomyces species.

A multi-phase multi-objective dynamic genome-scale model shows different redox balancing among yeast species in fermentation

The paper develops a dynamic genome-scale model to compare redox balancing strategies in yeast species during fermentation, revealing novel metabolic pathways in cryotolerant strains.

A multi-phase multi-objective genome-scale model shows diverse redox balance strategies in yeasts

This paper develops a dynamic genome-scale model to analyze redox balance strategies in yeasts during batch cultures, showing how cryotolerant strains achieve metabolic stability.