Fernando W. Rossine

This study shows that prophage induction via SOS response limits resistance evolution to DNA-damaging antibiotics by eliminating mutants with high DNA damage.

The paper identifies deletion-born gene fusions as a mechanism for novel gene emergence in bacteria, demonstrating their prevalence across the bacterial tree of life.

This study measures within-cell plasmid fitness and shows that incompatible plasmids co-occur longer due to methylation-based eclipsing, with less transcriptionally active plasmids having a selective advantage.

The paper demonstrates that RNA-guided nuclease TnpB enables gene drive in plasmids by biasing the inheritance of insertion sequences.