Daniel S. Eaton

This study measures within-cell plasmid fitness and shows that incompatible plasmids co-occur longer due to methylation-based eclipsing, with less transcriptionally active plasmids having a selective advantage.

The paper uses multi-generational imaging to study essential genes in E. coli, revealing new mechanisms behind growth laws and identifying unknown gene functions.

This paper introduces BatCRISPRi, a CRISPRi system in Bacillus subtilis that uses a rapamycin-dependent degron to eliminate leakiness and enable reversible gene knockdown.