Fabienne Pituello

CDC25B couples ribosome biogenesis to cell cycle kinetics to promote spinal cord neurogenesis

The paper shows CDC25B promotes spinal cord neurogenesis by coordinating cell cycle progression with ribosome biogenesis, leading to increased translation in differentiating neurons.

Control of G2 phase duration by CDC25B modulates the switch from direct to indirect neurogenesis in the neocortex

This study shows that CDC25B regulates G2 phase duration, affecting the balance between direct and indirect neurogenesis in the developing mouse neocortex.

G1 PHASE LENGTHENING DURING NEURAL TISSUE DEVELOPMENT INVOLVES CDC25B INDUCED G1 HETEROGENEITY.

The paper measures cell cycle phases in neural progenitor cells and identifies CDC25B as an indirect regulator of G1 phase lengthening during tissue development.

Mathematical modeling supports fate restriction in neurogenic progenitors of the embryonic ventral spinal cord

The paper develops a mathematical model to study fate restriction in neurogenic progenitors of the embryonic ventral spinal cord, showing that CDC25B may play a role in restricting progenitor divisions.

Neurogenic decisions require a cell cycle independent function of the CD25B phosphatase

This study shows CDC25B phosphatase regulates neuronal production in the neural tube independently of cell cycle dynamics in chick neural progenitors.

FGFs are orchestra conductors of Shh-dependent oligodendroglial fate specification in the ventral spinal cord

The paper shows FGF signaling is required for ventral oligodendrocyte precursor cell generation alongside Shh, with FGFs also regulating Shh signaling and Olig2 expression.