Cell-to-cell heterogeneity in Sox2 and Brachyury expression ratios guides progenitor destiny by controlling their motility.
Michèle Romanos, Guillaume Allio, Myriam Roussigné…·Bertrand Bénazéraf
The paper shows that variations in Sox2-to-Bra protein ratios in posterior progenitors influence their motility and fate, guiding their contribution to neural or mesodermal tissues.