Author

Bogdan M. Benin

Northeast Ohio Medical UniversityORCID 0000-0002-6502-8237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Trae Hillyer· 2 shared Woo Shik ShiniD· 2 shared Yuk Yin ShamiD· 2 shared A. M. Cmolik· 1 shared Belinda B. WillardiD· 1 shared Chuanqi SuniD· 1 shared Jeffrey D. MighioniD· 1 shared Noah AguirreiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Trae Hillyer

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Carbapenem-induced β-lactamase-isoform expression trends in Acinetobacter baumannii

Bogdan M. Benin, Trae Hillyer, Noah Aguirre, Yuk Yin Sham, Belinda B. Willard, Woo Shik Shin

This study shows that carbapenem exposure leads to concentration- and carbapenem-dependent trends in β-lactamase-isoform expression in Acinetobacter baumannii, suggesting non-stochastic resistance mechanisms.

Scientific Reports · Dec 27, 2024Peer-reviewedMicrobiology

Development of non-β-Lactam covalent allosteric inhibitors targeting PBP2a in Methicillin-Resistant Staphylococcus aureus

Bogdan M. Benin, Rupak Kharel, Trae Hillyer, Chuanqi Sun, A. M. Cmolik, Taylor S. Kuebler, Yuk Yin Sham, Robert A. Bonomo, Jeffrey D. Mighion, Woo Shik Shin

This study develops non-β-lactam covalent allosteric inhibitors targeting PBP2a in MRSA, showing enhanced cell inhibition and antimicrobial activity against resistant strains.

bioRxiv · May 29, 2024 · PreprintMicrobiology