Bundle-specific associations between white matter microstructure and Aβ and tau pathology at their connecting cortical endpoints in older adults at risk of Alzheimer's disease
Alexa Pichet Binette, Guillaume Theaud, François Rheault, Maggie Roy, D. Louis Collins, John C.S. Breitner, Judes Poirier, Maxime Descoteaux, Sylvia Villeneuve
The paper examines associations between white matter microstructure and Aβ/tau pathology in specific brain bundles in at-risk older adults, finding diffusion metrics linked to Aβ and tau levels at cortical endpoints.
bioRxiv · Aug 27, 2020 · PreprintNeuroscience