Robert S. Chapkin

This study shows that inhibiting FADS1 reduces renal cancer growth by inducing ER stress and ATF3-mediated responses, highlighting FADS1 as a therapeutic target.

This paper introduces spline-DV, a method to analyze variability in scRNA-seq data, identifying genes with differential expression variability in conditions like obesity and cancer.

scTenifoldKnk predicts gene function via virtual knockout using scRNA-seq data from wild-type samples, recapitulating real-animal KO results.

The paper introduces a Bayesian classifier for 16S rRNA metagenomic data, showing it outperforms existing methods when sample size to dimensionality ratio is small.