Author

Tomoka Takao

Okayama UniversityORCID 0000-0002-6519-2301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Assay:organoid / primary culture· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Takeshi TakaradaiD· 4 shared Tatsunori Osone· 4 shared Shigeo Otake· 2 shared Yuki Fujisawa· 2 shared Daisuke YamadaiD· 1 shared Eiji NakataiD· 1 shared Hiroomi OkuyamaiD· 1 shared Junya ToguchidaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersBioinformatics

Takeshi TakaradaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

The Role of Human-Specific lncRNA in Hyaline Cartilage Development

Tatsunori Osone, Tomoka Takao, Takeshi Takarada

This study identifies human-specific lncRNAs upregulated in hyaline cartilage-like tissue derived from human iPS cells, suggesting their role in regulating extracellular matrix genes and potential applications in regenerative medicine.

bioRxiv · Feb 18, 2026 · PreprintBioinformatics

SGCRNA: Spectral Clustering-Guided Co-Expression Network Analysis Without Scale-Free Constraints for Multi-Omic Data

Tatsunori Osone, Tomoka Takao, Shigeo Otake, Takeshi Takarada

SGCRNA improves upon WGCNA by removing scale-free constraints and parameter tuning, offering a more flexible co-expression network analysis for multi-omic data.

Briefings in Bioinformatics · Jan 1, 2026Peer-reviewedBioinformatics

Scaffold-free cryopreservable cartilage grafts obtained from hiPSC-derived chondroprogenitor cells for airway reconstruction with growth adaptability

Shojiro Hanaki, Tomoka Takao, Yuki Fujisawa, Tomoyuki Ota, Tatsunori Osone, Shigeo Otake, Ryosuke Iwai, Koichi Deguchi, Kazuhiro Yamamoto, Hiroomi Okuyama, Takeshi Takarada

This study develops scaffold-free, cryopreservable cartilage grafts from hiPSC-derived cells for tracheal reconstruction, showing growth adaptability and superior performance in animal models.

bioRxiv · Jun 5, 2025 · PreprintBioengineering

Modeling human limb skeletal development using human pluripotent stem cell-derived skeletal assembloids

Tomoka Takao, Tatsunori Osone, Kohei Sato, Daisuke Yamada, Yuki Fujisawa, Masaya Hagiwara, Eiji Nakata, Toshifumi Ozaki, Junya Toguchida, Takeshi Takarada

This study develops a method to generate human skeletal assembloids that recapitulate limb skeletal development and endochondral ossification with longitudinal growth.

bioRxiv · Jan 9, 2025 · PreprintBioengineering