Author

Shikhar Prakash

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Madhur SrivastavaiD· 2 shared Alexa Albert· 1 shared Amanda L. WoermaniD· 1 shared Athena Quddus· 1 shared Baptiste FischeriD· 1 shared Clara PierssoniD· 1 shared Karen TsayiD· 1 shared Matthew P. FrostiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Madhur SrivastavaORCID

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2 papers

Recent·Most cited

Development of an EPR-based methodology to study protein-lipid interaction

Clara Piersson, Shikhar Prakash, Victoria Lublin, Melanie Rossotti, Baptiste Fischer, Madhur Srivastava, Yann Fichou

This paper develops an EPR-based method to quantify protein-lipid interactions, demonstrating its ability to measure binding affinity and concentration of Tau protein with lipids.

Biophysical Chemistry · Nov 8, 2025Peer-reviewedBiophysics

Passaging Human Tauopathy Patient Samples in Cells Generates Heterogeneous Fibrils with a Subpopulation Adopting Disease Folds

Zhikai Zeng, Karen Tsay, Vishnu Vijayan, Matthew P. Frost, Shikhar Prakash, Athena Quddus, Alexa Albert, Michael P. Vigers, Madhur Srivastava, Amanda L. Woerman, Songi Han

The paper shows that cell-passaged tau fibrils from CBD and PSP patients generate heterogeneous fibrils with a subpopulation resembling the original disease fold.

bioRxiv · Jul 19, 2023 · PreprintMolecular Biology