Gabriel Núñez

Butyrate extends health and lifespan in mice with mitochondrial deficiency

This study shows that butyrate supplementation improves health and extends lifespan in mice with mitochondrial dysfunction by restoring intestinal barrier function and epigenetic marks.

Breastmilk antibody isotypes differentially protect against neonatal rotavirus infection and modulate the timing and clonal architecture of offspring B cell responses

This study shows maternal IgA protects against neonatal rotavirus infection while maternal IgG delays humoral immunity development, demonstrating passive immunity's dual role in immediate protection and long-term immune education.