Author

Moustafa M. Saleh

Indiana University BloomingtonORCID 0000-0002-6531-5711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Gabriel E. ZentneriD· 3 shared Didier DevysiD· 2 shared Jason P. Tourigny· 2 shared Kenny Schumacher· 2 shared Celia JerónimoiD· 1 shared François RobertiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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3 shared papersGenetics

Gabriel E. ZentnerORCID

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3 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedAug 12, 2021

Connection of core and tail Mediator modules restrains transcription from TFIID-dependent promoters

Moustafa M. Saleh, Celia Jerónimo, François Robert, Gabriel E. Zentner

The paper investigates the effects of separating Mediator modules on transcription, finding that tail/cMed disconnection leads to overactivation of TFIID-dependent genes and underactivation of SAGA-requiring genes.

17 citations

statistical modelexperimental assay

𝕏 PostBluesky

GenomicsGeneticsPeer-reviewedJan 7, 2021

Architectural Mediator subunits are differentially essential for global transcription in yeast

Jason P. Tourigny, Kenny Schumacher, Moustafa M. Saleh…·Gabriel E. Zentner

The paper shows that Med14 and Med17 subunits of the Mediator complex are essential for transcription in yeast, with Med17 having a more severe impact.

16 citations

yeastexperimental assay

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Molecular BiologyMolecular and Cellular BiologyPeer-reviewedSep 28, 2018

Mediator is essential for small nuclear and nucleolar RNA transcription in yeast

Jason P. Tourigny, Moustafa M. Saleh, Kenny Schumacher…·Gabriel E. Zentner

The paper shows that the Mediator complex is required for sn/snoRNA transcription in yeast, similar to its role in mRNA transcription.

9 citations

yeastDNA methylation

𝕏 PostBluesky