Serena H. Chen

Enhancing Protein Binding Site Residue Prediction with Graph Neural Networks: Impacts of Cutoff Distance and Feature Selection

This study evaluates how cutoff distance and feature selection affect protein binding site residue prediction using graph neural networks across four eukaryotic organisms.

Integrated Spatial Analysis of Ovarian Precancerous Lesions

The paper identifies four subtypes of ovarian precancerous lesions and links them to genetic and molecular features associated with cancer progression.

Identification and characterization of substrate- and product-selective nylon hydrolases

The paper identifies and characterizes diverse nylon hydrolases, showing that 40% of tested enzymes have significant activity, with some showing substrate selectivity for Nylon 6,6 over Nylon 6.

Evaluating genetic ancestry and self-reported ethnicity in the context of carrier screening

The paper evaluates the reliability of self-reported ethnicity versus genetic ancestry in carrier screening and finds discrepancies that affect carrier risk estimation.