Dana L. Carper

This paper investigates how engineered Pseudomonas putida reconfigures metabolic fluxes to enhance muconate production from lignin-related aromatics.

This study uses genome shuffling in Bacillus subtilis to map quantitative trait loci for complex phenotypes, identifying high-confidence QTLs of moderate size.

This study identifies cellular stress tolerance as a key factor in genetic transformability of Candida species and develops a method to improve CRISPR screening efficiency.

This study characterizes three nylon hydrolases, identifying structural features and activity differences that inform their substrate specificity and potential for engineering.

This paper demonstrates a method to produce higher-molecular-weight nylons using chemically-synthesized diads and biosynthetic amide synthetases, expanding the range of usable precursors.

This study optimizes reaction conditions for three nylon-degrading enzymes, achieving high product titers for PA6 and PA66 without enzyme engineering or substrate pretreatment, and demonstrates scalability for complex PA-based materials.

This study demonstrates that NIS synthetases can synthesize sequenced oligoamides from unprotected substrates, enabling the creation of novel sequence-defined polyamides with improved properties.

This study uses longitudinal proteomics to analyze how Staphylococcus aureus reallocates resources during phage infection, revealing mechanisms of host defense and phage evasion.

The paper identifies and characterizes diverse nylon hydrolases, showing that 40% of tested enzymes have significant activity, with some showing substrate selectivity for Nylon 6,6 over Nylon 6.

This paper identifies ECM29 as a key protein mediating microbial enhancement of plant heat stress tolerance through proteasome modulation in Arabidopsis.

This study uses CRISPRi screens to identify transcriptional gradients in Synechococcus sp. PCC 7002 that improve growth under cold monochromatic light conditions.

This study uses experimental evolution to identify mutations that enhance catabolism of a lignin-derived aromatic dimer in Novosphingobium aromaticivorans, revealing a key enzyme involved in its degradation.