Cancer BiologybioRxivPreprint
Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death
Garcia Céline, Roussel Louis, M Sarah…·Aubin Penna
This study shows that GNAQ/11 mutations in uveal melanoma alter IP3 receptor expression, protecting cells from calcium-driven death while promoting proliferation.
DOI 10.1101/2024.11.25.625282