Systems BiologyScience AdvancesPeer-reviewed
Gene Regulatory Network topology governs resistance and treatment escape in glioma stem-like cells
James Hugh Park, Parvinder Hothi, Adrián López García de Lomana…·Nitin S. Baliga
The paper shows how gene regulatory network topology in glioma stem-like cells influences drug resistance and treatment escape, suggesting strategies to overcome resistance through combinatorial therapies.