Author

Sonia Sharma

La Jolla Institute for ImmunologyORCID 0000-0002-6556-1963Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sonia Sharma3 papers · The University of Melbourne

Biology Disciplines

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Immunology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alicia GibbonsiD· 3 shared Mahati RayadurgamiD· 3 shared Maija CoreyiD· 3 shared Priyanka SaminathaniD· 3 shared Camille FangiD· 2 shared Carolina Altbaum· 2 shared Mousa VatanmakanianiD· 2 shared Namratha NadigiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Alicia GibbonsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LPC 18:2-Driven Apoptosis In Neutrophils Is Non-Inflammatory and Lipid Raft Dependent

Priyanka Saminathan, Alicia Gibbons, Ian T. Mathews, Maija Corey, Ashmitaa Logandha Ramamoorthy Premlal, Mahati Rayadurgam, Namratha Nadig, Camille Fang, Neha Reddy, Mousa Vatanmakanian, Carolina Altbaum, Sonia Sharma

This study compares the effects of LPC 18:2 and LPC 16:0 on neutrophil apoptosis, showing LPC 18:2 induces non-inflammatory, lipid raft-dependent apoptosis while LPC 16:0 causes inflammatory pyroptosis.

Frontiers in Immunology · Jul 31, 2026Peer-reviewedImmunology

Deoxyguanosine Kinase Deficiency Couples Purine Metabolism to Innate Immune Activation and Lipid Accumulation in Hepatocytes

Maija Corey, Mahati Rayadurgam, Mousa Vatanmakanian, Alicia Gibbons, Carolina Altbaum, Jeamin Jung, Neha Reddy, Priyanka Saminathan, Kiyokazu Kakugawa, Sonia Sharma

This study shows DGUOK deficiency disrupts purine metabolism, leading to lipid accumulation and innate immune activation in hepatocytes, independent of mtDNA depletion.

The Journal of Immunology · Jul 15, 2026Peer-reviewedImmunology

Unmasking Early Microglial Remodeling in an Alzheimer's Disease Mouse Model

Priyanka Saminathan, Sara McArdle, Maija Corey, Namratha Nadig, Camille Fang, Alicia Gibbons, Mahati Rayadurgam, Sonia Sharma

The paper quantifies early microglial structural changes in 5xFAD mice before amyloid plaques, revealing sex-specific differences and a link between morphology and phagolysosomal activity.

Frontiers in Cellular Neuroscience · Jan 2, 2026Peer-reviewedNeuroscience